Medicinal chemists prepare and/or select appropriate compounds for biological evaluation that, if found to be active, could serve as LEAD COMPOUNDS. They then evaluate the STRUCTURE–ACTIVITY RELATIONSHIPS (SARs) of analogous compounds with regard to their in vitro and in vivo Read More …
Author: Utsab Debnath
Why Alumni Association is needed in Universities / Institutions ?
The reputation of any educational institution depends upon good results, co-curricular activities, environment, and investments. But there is one factor which only requires support and encouragement and brings strength and expansion to the institution’s reputation and progress and that factor Read More …
Structure-Based Drug Design (SBDD) : Positive Approach For Drug Discovery
Structure-based drug design is one of several methods in the rational drug design toolbox. Drug targets are typically key molecules involved in a specific metabolic or cell signaling pathway that is known, or believed, to be related to a particular Read More …
HIV drugs reach 8 mn people in needy countries
More than eight million people — a record number in low- and middle-income countries — are now receiving antiretroviral drugs to treat HIV, according to data released Wednesday by UNAIDS. The rise in drug coverage was accompanied by a dramatic Read More …
Aromatase (CYP19), a cytochrome P450 play an important role in breast tumour promotion
Estrogens play an important role in breast cancer development. Aromatase (CYP19), a cytochrome P450, is the enzyme that synthesizes estrogens. Through cell culture studies, it has been seen that in situ produced estrogen plays a more important role than circulating Read More …